SPDP-PEG8-tBu ester


SPDP-PEG8-tBu ester is an SPDP derivative bearing a PEG spacer with t-butyl ester end group. The pyridyldithiol reactive groups can react cysteine sulfhydryls with to form cleavable (reducible) disulfide bonds, which makes it an ideal conjugate tool for cysteine residues.

Axispharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.

Section I. Identification of the substance

Product Name: SPDP-PEG8- tBu ester
Catalog number: AP-10037
Supplier: AxisPharm, 9823 Pacific Heights Blvd , Suite F , Sa n Diego , CA 92121
Tel: 1-858-677-9432, Email : sales@axispharm.com

Section II. Hazards identi fication

GHS — Classification
Classification – No t clas sifie d as a haz ar d

Section III. Composition and in forma tion on ingred ients.

Name: SPDP-PEG8 -tBu ester
Formu la: C31H5 4N2O11S 2
MW: 694.9

Section IV. First aid measures

1. Skin contact: Immediately wash skin with cop ious amounts of water fo r at least 15
minutes while removing contamina ted clothing and s hoes. If irrita tion
persists, seek medical attention.
2. Eye contact : Immediately wash skin with copious amounts of water fo r at least 15
minutes. Assure adequate flushing of the eyes by separating the eyelids with
fingers. If irrita tion persists, seek medical attention.
3. Inhalation: Remove to fresh air. In severe cases or if symptoms persist, seek medical
attent ion.
4. Ingestion: Wash out mouth with copious amounts of water for at least 15 minutes. Seek
medical atte ntion.

Section V. Firefigh ting measures

In the eve nt of a fire involving this material , alone or in combination with other mate rials,
use dry powder or carbon dioxide e xtingu ishe rs. Protective clothing and self -contained
breathing apparatus should be worn.

Section VI. Accidental release measures

Personal precautions : Wear suitable personal p rotective equipme nt whic h perfo rms satisfactorily
and meets local/state/national sta ndards.
Respirato ry precaution: Wear approved mask/respirato r
Ha nd precaution: Wear suitable gloves/gauntlets
Skin protection: Wear suitable protective clothing
Eye protection: Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar ine rt absorbe nt material , sweep up and
keep in a tight ly closed container fo r disposal. See section 12.
Environmental precaut ions: Do no t allow mate rial to ente r drains or water courses.

Section VII. Handling and storage

Handling: T his product shou ld be ha ndled only by, or unde r the close supervision of, those
properly quali fied in the ha ndling a nd use of potentially haza rdous chemicals, who
should take into account the fi re, health a nd chemical ha zard data give n on this

Section VIII. Exposure Contro ls / PPE

Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear chemical-resista nt gloves, safety goggles.
General hygiene measures: Wash tho roughly after ha ndling. Was h contaminated clothing
before reuse.

Section IX. Physical and chemical properties

Appearance : liquid
Odor: No data
Boiling point: No data
Melting point : No data
Flash point: No data
Density: No data
Mole cular formula: C31H54N2O1 1S2
Mole cular weight: 694.9

Section X. Stabil ity and reactiv ity

Conditions to avoid: Heat , flames and sparks.
Materials to avoid: Oxidizing age nts.
Possible hazardous combustion products: No data available.

Section XI. Toxicological informa tion

No data

Section XII. Ecological information

No data

Section XIII. Disposal consideration

Arra nge disposal as special waste, by licensed disposal compa ny, i n consultation with local
waste disposal authori ty, in accorda nce wi th nat ional and re gional re gulations.

Section XIV. Transporta tion in forma tion

Non-haza rdous for air a nd ground tra nspo rtation.

Section XV. Regulatory informat ion

Indication of Danger: No data.
Risk Statement: No data.
Safety Statement: In case of contact with eyes, rinse immediately with ple nty of water a nd seek
medical advice. Wear suitable gloves and eye/face protection.

Section XVI. Other in forma tion

This MSDS is correct to the best of our knowledge a nd belief at the date of its publication
but does not purpor t to be all inclusive and shal l be used only as a guide. AxisPha rm shal l
not be held liable for a ny loss, injury or dama ge whic h may result from its use. This
product is for research a nd developme nt use only.