The maleimide group reacts specifically with a thiol group to form a covalent C-S bond, enabling the bioconjugation with a thiol bearing molecules. The end oxyamine group can react specifically with an aldehyde to form a reversible oxime bond. If reduced, the oxime can be converted to a stable carbon-N bond. The PEG spacer increase the solubility of the resulting complex in aqueous media.
Axispharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
Section I. Identification of the subs tance
Product Name: Mal-amide-PEG2 -oxyamine
Catalog number: AP-10062
Supplier: AxisPharm, 9823Pacific Heights Blvd, Suite F , San D iego, CA 92121
Tel: 1 -858-677-9432, Email: sales@axispharm.com
Section II. Hazards identification
GHS—Classification
Classification – No t class ifieda sahaz ard
Section III. Composition and informat ion on ingredients.
Name: Mal-amide-PEG2 -oxyamine
Fo rmu la : C13H21N3O 6
MW: 315.32
CAS:
Section IV. First aid measures
1. Skincontact:Immediately
washskinwithcopiou samountsofwaterforatlea st15
minuteswhileremovingcontaminatedclothingandshoes.Ifirritation
persists, seek medicalattention.
2. Eye contact: Immedia tely wash skin with copiou s amounts of water for at least 15
minutes. Assureadequateflushingoftheeyesbyseparatingtheeyelidswith
fingers. If irritation persists, seek medicalattention.
3. Inhalation: Removetofreshair.Insevereca sesor ifsymptomspersist,seekmedical
attention.
4. Ingestion: Washoutmouthwithcopiou samountsofwaterforatleast15minutes.Seek
medicala ttention.
Section V. Firefighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing
apparatu s should be worn.
Section VI. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily
and meets local/state/national standards .
Respiratory precaution: Wear approved ma sk/respirator
Hand precaution: Wear suitable gloves/gauntlets
Skin protection: Wear suitable protective clothing
Eye protection: Wear suitable eye protection
Methods for cleaning up:Mix with sand or similar inert absorbent material, sweep up and
keep in a tightly closed container for disposal. See section 12.
Environmental precautions: Do not allow ma ter ial to enter drains or water courses.
Section VII. Handling and s torage
Handling: This product should be handled only by, or under the close supervision of, those
properly qualified in the handling and use of potentially hazardou s chemicals, who
should take into account the fire, health and chemical hazard data given on this
sheet.
Section VIII. Exposure Controls / PPE
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear chemical -resistant gloves, sa fety goggles.
General hygiene measures: Wash thoroughly a fter handling. Wa sh contaminated clothing
beforereu se.
Section IX.Physicalandchemicalproperties
Appearance:
liquidOdor: No data
Boilingpoint: Noda ta
Melting point: No data
Flash point: No data
Density: No data
Molecular formula: C13H 21N3O6
Molecular weight: 315.32
Section X. Stability and reactivity
Conditions to avoid: Heat, flames and spark s.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: No data available.
Section XI. Toxicological information
No data
Section XII. Ecological information
No data
Section XIII. Disposal cons iderat ion
Arrange disposal a s special wa ste, by licensed disposal company, i n consultation with local
wa ste disposal authority, in accordance with na tional and regional regulations.
Section XIV. Transportation informat ion
Non-hazardou s for air and ground transportation.
Section XV. Regulatory information
Indication of Danger: No data.
Risk Statement: No data.
Safety Statement: In case of contact with eyes, rinse immedia tely with plenty of wat er and seek
medical advice. Wear suitable gloves and eye/face protection.
Section XVI. Other information
This MSDS is correct to the best of our knowledge and belief a t the date of its publication
but does not purport to be all inclu sive and shall be used only as a guide. AxisPharm shall
not be held liable for any loss, injury or damage which may result from its use. This
product is for research and development u se only.
