Azido-PEG24-Hydrazide contains an azide group and a terminal hydrazide group. The hydrophilic PEG spacer can increase solubility of a compound in aqueous media. The azide group readily reacts with alkyne, BCN, DBCO through Click Chemistry to yield a stable triazole linkag. The hydrazide group can be reacted with an aldehyde or ketone to form a hydrozone bond that are reversible under acidic conditions. The reversibility of spacer has been widely utilized to for payload traffiking and release.
Axispharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
Section I. Identification of the subs tance
Product Name: N3 -PEG24-Hydrazide
Catalog number: AP-10271
Supplier: AxisPharm, 9823 Pacific Heights Blvd, Suite F, San Diego, CA 92121
Tel: 1 -858-677-9432, Email: firstname.lastname@example.org
Section II. Hazards identification
Classification – No t cl ass ified a s a haz ard
Section III. Composition and informat ion on ingredients.
Fo rmu la : C47H99N5O25
Section IV. First aid measures
1. Skin contact: Immediately wa sh skin with copiou s amounts of wa ter for at lea st 15
minutes while removing contaminated clothing and shoes. If
irritation persists, seek medical attention.
2. Eye contact: Immedia tely wash skin with copiou s amounts of water for at least 15
minutes. Assure adequate flu shing of the eyes by separating the eyelids
with fingers. If irritation persists, seek medical attention.
3. Inhalation: Remove to fresh air. In severe ca ses or if symptoms persist, seek
4. Ingestion: Washoutmouthwithcopiou samountsofwaterforatleast15minutes.Seek
Section V. Firefighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self -contained breathing
apparatu s should be worn.
Section VI. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily
and meets local/state/national standards.
Respiratory precaution: Wear approved ma sk/respirator
Hand precaution: Wear suitable gloves/gauntlets
Skin protection: Wear suitable protective clothing
Eye protection: Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent mater ial, sweep up and
keep in a tightly closed container for disposal. See section 12.
Environmental precautions: Do not allow ma ter ial to enter drains or water courses.
Section VII. Handling and s torage
Handling: This product should be handled only by, or under the close supervision of, those
properly qualified in the handling and use of potentially hazardou s chemicals, who
should take into account the fire, health and chemical hazard data given on this
Section VIII. Exposure Controls / PPE
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear chemical -resistant gloves, sa fety goggles.
General hygiene measures: Wash thoroughly a fter handling. Wa sh contaminated clothing
before reu se.
Section IX. Phys ical and chemical properties
Odor: No data
Boilingpoint: No data
Melting point: No data
Flash point: No data
Density: No data
Molecular formula: C47H99N5O25
Molecular weight: 1186.34
Section X. Stability and reactivity
Conditions to avoid: Heat, flames and spark s.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: No data available.
Section XI. Toxicological information
Section XII. Ecological information
Section XIII. Disposal cons iderat ion
Arrange disposal a s special wa ste, by licensed disposal company, i n consultation with local
wa ste disposal authority, in accordance with na tional and regional regulations.
Section XIV. Transportation informat ion
Non-hazardou s for air and ground transpor tation.
Section XV. Regulatory information
Indication of Danger: No data.
Risk Statement: No data.
Safety Statement: In case of contact with eyes, rinse immedia tely with plenty of water and seek
medical advice. Wear suitable gloves and eye/face protection.
Section XVI. Other information
This SDS is correct to the best of our knowledge and belief at the date of it s publication but
does not purport to be all inclu sive and shall be used only as a guide. AxisPharm shall not
be held liable for any loss, injury or damage which may result from its use. This product is
for research and development u se only.